Dichloromethane HPLC 2.5L

R3,959.44 Incl VAT

Availability: 49 in stock (can be backordered)

Add to Wishlist
Add to Wishlist
SKU: HPLC-D1 Category:

Dichloromethane HPLC – Identification of Product
Chemical Code: HPLC-D1
Chemical Name: Dichloromethane
Chemical Grade: HPLC
Chemical Formula: CH₂Cl₂
Chemical Weight: 84,93 g/mol
CAS No: 75-09-2
Chemical Synonyms: Methylene Chloride, DCM.

Dichloromethane HPLC – Hazards Identification
REACH No: 01-2119480404-41-XXXX
Signal Word: Warning
Supplemental Hazard Information:
Additional Hazard Information: This substance contains no components considered to be either persistent, bio-accumulative and toxic (PBT), or very persistent and very bio-accumulative (vPvB) at levels of 0.1% or higher.

Dichloromethane HPLC – Hazards statements
H315 – Causes skin irritation.
H319 – Causes serious eye irritation.
H336 – May cause drowsiness or dizziness.
H351 – Suspected of causing cancer.

Dichloromethane HPLC – Precautionary statements
P201 – Obtain special instructions before use.
P302 + P352 – IF ON SKIN: Wash with plenty of water.
P305 + P351 + P338 – IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P313 – IF exposed or concerned: Get medical advice/ attention.

Dichloromethane HPLC – Composition of Chemical
Chemical Formula: CH₂Cl₂
EC No 1272/2008: 01-2119480404-41-XXXX

Dichloromethane HPLC – First Aid Measures
General Advice: Consult a physician. Show this safety data sheet to the doctor in attendance.
If: Inhaled: If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
If: Skin Contact: Wash off with soap and plenty of water. Consult a physician.
If: Eye Contac: Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If: Swallowed: Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Important Symptoms: The most important known symptoms and effects are described in the labeling section.
Immediate Medical Attention: No Data Available

Firefighting Measures
Extinguishing Media: Use Water spray, Alcohol-resistant foam, Dry chemical or Carbon Dioxide.
Hazards Arising: Carbon Oxides, Hydrogen Chloride gas.
Advice for Firefighters: Wear self-contained breathing apparatus for firefighting if necessary.
Info for Firefighting: No Data Available

Dichloromethane HPLC – Accidental Release Measures
Personal Precautions: Use personal protective equipment. Avoid breathing vapours, mist or gas.
Ensure adequate ventilation.
Evacuate personnel to safe areas.
Enviromental Precautions: Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Method for Containment: Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and Storage
Personal Precautions: Avoid contact with skin and eyes.
Avoid inhalation of vapour or mist.
Enviromental Precautions: Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Heat sensitive.
Handle and store under inert gas.
Exposure Controls | Personal Protection
Derived No Effect Level (DNEL)
Workers | Application Area | Exposure Routes | Health Effect | Value
Workers – Inhalation – Acute systemic effects – 706 mg/m3
Workers – Inhalation – Long-term systemic effects – 353 mg/m3
Workers – Skin contact – Long-term systemic effects – 4750mg/kg BW/d
Consumers | Application Area | Exposure Routes | Health Effect | Value
Consumers – Ingestion – Long-term systemic effects – 0,06mg/kg BW/d
Consumers – Inhalation – Long-term systemic effects – 88,3 mg/m3
Consumers – Skin contact – Long-term systemic effects – 2395mg/kg BW/d
Consumers – Inhalation – Acute systemic effects – 353 mg/m3
Predicted No Effect Concentration (PNEC)
Soil – 0,583 mg/kg
Marine water – 0,194 mg/l
Fresh water – 0,54 mg/l
Marine sediment – 1,61 mg/kg
Fresh water sediment – 4,47 mg/kg
Onsite sewage treatment plant – 26 mg/l
Aquatic intermittent release – 0,27 mg/l
Engineering Controls: Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday Eye/Face Protection: Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin Protection: Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching gloves outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU
Directive 89/686/EEC and the standard EN 374 derived from it.
Splash contact –
Material: Fluorinated rubber. Minimum layer thickness: 0,7 mm
Break through time: 148 min. Material tested: Vitoject®
Data source: KCL GmbH, D-36124. Test method: EN374.
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Body Protection: Complete suit protecting against chemicals. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory Protection: Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multipurpose combination type OV/AG (US) or type ABEK (EU EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Physical and Chemical Properties
Appearance: Clear, volatile liquid
Odour: of Chloroform
Odour Threshold: No Data Available
pH: No Data Available
Melting Point: Melting point/range: -97 °C
Boiling Point: 39,8 – 40 °C
Flash Point: No Data Available
Evaporation: 0,71
Flammability: No Data Available
Upper/Lower Flammability or Explosive Limits: Upper explosion limit: 19 %(V),
Lower explosion limit: 12 %(V).
Vapour pressure: 470,9 hPa at 20,0 °C
Vapour density: 2,93 – (Air = 1.0)
Relative density: 1,325 g/mL at 25 °C
Water solubility: MisciblePartition Coefficien: log Pow: 1,25
Auto-ignition Temperature: 605 °C (at 1.013 hPa – DIN 51794)
Decomposition Temperature: No Data Available
Viscosity: No Data Available
Explosive properties: No Data Available
Oxidizing properties: No Data Available
Other Safety Info: Relative vapour density 2,93 – (Air = 1.0)

Stability and Reactivity
Reactivity: No Data Available
Chemical Stability: Stable under recommended storage conditions.
Possibility of hazardous reactions: No Data Available
Conditions to Avoid: Heat, flames and sparks.
Exposure to sunlight.
Incompatible Materials: Alkali Metals, Aluminum, Strong oxidizing agents, Bases, Amines, Magnesium, Strong Acids, Vinyl compounds, Various plastics, Rubber, Light metals, Metals, Mild steel.
Hazardous Decomposition Products: Hazardous decomposition products formed under fire conditions – Carbon Oxides, Hydrogen Chloride Gas

Toxicological Information
Acute Toxicity: LD50 Oral – Rat – male and female – > 2.000 mg/kg (OECD Test Guideline 401).
LC50 Inhalation – Mouse – 4 h – 86 mg/l Remarks: (ECHA).
LD50 Dermal – Rat – male and female – > 2.000 mg/kg (OECD Test Guideline 402).
Skin Corrosion/Irritation: Rabbit –
Result: Irritations – 4 h – (OECD Test Guideline 404).
Repeated or prolonged exposure may cause skin irritation and dermatitis, due to degreasing properties of the product.
Serious Eye damage | Eye Irritation: Rabbit –
Result: Eye irritation – Remarks: (ECHA).
Risk of corneal clouding.
Cell Mutagenicity: Mutagenicity (mammal cell test): Chromosome aberration –
Chinese hamster ovary cells – Result: positive.
Ames test – Salmonella typhimurium – Result: positive.
(OECD Test Guideline 474)
Mouse – male and female – Bone marrow
Result: negative
Carcinogenicity: Limited evidence of carcinogenicity in animal studies.
Suspected human carcinogensIARC: 2A – Group 2A: Probably carcinogenic to humans (Methylene Chloride)
Reproductive toxicity: No Data Available
Specific Target Organ Toxicity – Single Exposure: May cause respiratory irritation.
May cause drowsiness or dizziness.
Specific Target Organ Toxicity – Repeated Exposure: Inhalation – May cause damage to organs through prolonged or repeated exposure – Central nervous system
Acute oral toxicity – Nausea, Vomiting, Risk of aspiration upon vomiting.
Aspiration may cause pulmonary oedema and pneumonitis.
Acute inhalation toxicity – Possible damages: Mucosal irritations
Aspiration Hazard: No Data Available

Ecological Information
Ecological Toxicity: Toxicity to fish:
Flow-through test LC50 – Pimephales promelas (fathead minnow) – 193,00 mg/l – 96 h. Remarks: (ECHA).
Toxicity to daphnia and other aquatic invertebrates:
Static test LC50 – Daphnia magna (Water flea) – 27 mg/l – 48 h (US-EPA).
Toxicity to bacteria:
Static test EC50 – activated sludge – 2.590 mg/l – 40 min. (OECD Test Guideline 209)
Ecological Persistence and degradability: Biodegradability aerobic – Exposure time 28 d
Result: 68 % – Readily biodegradable.
(OECD Test Guideline 301D)
Bioaccumulative Potential: Bio-accumulation:
Cyprinus carpio (Carp) – 6 Weeks – 250 ?g/l (Methylene Chloride).
Bio-concentration factor (BCF): 2 – 5,4 (OECD Test Guideline 305).
Cyprinus carpio (Carp) – 6 Weeks – 25 ?g/l (Methylene Chloride).
Bio-concentration factor (BCF): 6 – 40 (OECD Test Guideline 305).
Mobility in Soil: No Data Available
Results of PBT and vPvB Assessment: This substance contains no components considered to be either persistent, bio-accumulative and toxic (PBT), or very persistent and very bio-accumulative (vPvB) at levels of 0.1% or higher.
Other Adverse Effect: No Data Available

Disposal Considerations
Waste Treatment Methods: Product –
Offer surplus and non-recyclable solutions to a licensed disposal company. Waste material must be disposed of in accordance with the Directive on waste 2008/98/EC as well as other national and local regulations. Leave chemicals in original containers. No mixing with other waste. Handle uncleaned containers like the product itself. Contaminated packaging – Dispose of as unused product.

Transport Information
UN Number: ADR/RID: 1593
IMDG: 1593
IATA: 1593
IATA: Dichloromethane
Transport Hazard Class: ADR/RID: 6.1
IMDG: 6.1
IATA: 6.1
Packaging Group: ADR/RID: III
Enviromental Hazards: ADR/RID: no
IMDG Marine pollutant: no
IATA: no
Special Precautions: No Data Available
Regulatory Information
Safety, Health and environmental regulations: This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
Authorisations and/or restrictions on use:
REACH – Restrictions on the manufacture, placing on the market and use of certain dangerous substances, preparations and articles (Annex XVII): Methylene Chloride
Chemical Safety Assessment: A Chemical Safety Assessment has been carried out for this substance
Additional Info: RTECS: PA8050000
Repeated dose toxicity – Rat – male and female – Oral – 104 Weeks – No observed adverse effect level – 6 mg/kg.
Repeated dose toxicity – Rat – male and female – Inhalation – 104 Weeks.
Dizziness, Nausea, Vomiting, Narcosis, Cough, Irritant effects, Unconsciousness, Shortness of breath, Respiratory paralysis, Somnolence, Depressed respiration, CNS disorders, Inebriation.
Risk of corneal clouding.
The following applies to aliphatic halogenated hydrocarbons in general –
Systemic effect: Narcosis, Cardiovascular disorders.
Toxic effect on liver, kidneys.Dichloromethane is metabolized in the body producing Carbon Monoxide which increases and sustains carboxyhemoglobin levels in the blood, reducing the Oxygen-carrying capacity of the blood.
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.

The information stated above is considered to be correct, but does not claim to be inclusive and shall only be used as a guideline. The information provided by this document is confirmed by our continuous updating of knowledge and adheres to the products appropriate safety precautions. It does not represent any guarantee of the product’s
properties. RLS Chemicals and its Associates shall not be held accountable for any damage’s consequent of handling the above product

Shopping Cart
Scroll to Top
× How can I help you?