Diethyl Ether – Identification of Product
Chemical Code: CHE-D1
Chemical Name: Diethyl Ether
Chemical Formula: C₄H₁₀O
Chemical Weight: 74,12 g/mol
CAS No: 60-29-7
Chemical Synonyms: Ether, Ethyl Ether.
Diethyl Ether – Hazards Identification
REACH No: No Data Available
Signal Word: Danger
Supplemental Hazard Information: EUH019 – May form explosive peroxides.
EUH066 – Repeated exposure may cause skin dryness or cracking.
Additional Hazard Information: This substance contains no components considered to be either persistent, bio-accumulative and toxic (PBT), or very persistent and very bio-accumulative (vPvB) at levels of 0.1% or higher.
Diethyl Ether – Hazards statements
H224 – Extremely flammable liquid and vapour.
H302 – Harmful if swallowed.
H336 – May cause drowsiness or dizziness.
P210 – Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P301 + P312 + P330 – IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
P403 + P233 – Store in a well-ventilated place. Keep container tightly closed.
Diethyl Ether – Composition of Chemical
Chemical Formula: C₄H₁₀O
EC No 1272/2008: No Data Available
Diethyl Ether – First Aid Measures
General Advice: Consult a physician. Show this safety data sheet to the doctor in attendance.
If: Inhaled: If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
If: Skin Contact: Wash off with soap and plenty of water. Consult a physician.
If: Eye Contac: Flush eyes with water as a precaution.
If: Swallowed: Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Important Symptoms: The most important known symptoms and effects are described in the labeling section.
Immediate Medical Attention: No Data Available
Extinguishing Media: Suitable extinguishing media – Dry powder, Dry sand.
Unsuitable extinguishing media – Do NOT use water jet.
Hazards Arising: Carbon Oxides
Advice for Firefighters: Wear self-contained breathing apparatus for firefighting if necessary.
Info for Firefighting: Use water spray to cool unopened containers.
Accidental Release Measures
Personal Precautions: Use personal protective equipment.
Avoid breathing vapours, mist or gas.
Ensure adequate ventilation.
Remove all sources of ignition.
Evacuate personnel to safe areas.
Beware of vapours accumulating to form explosive concentrations.
Vapours can accumulate in low areas.
Enviromental Precautions: Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Method for Containment: Contain spillage, and then collect with non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite) and place in container for disposal according to local / national regulations.
Handling and Storage
Personal Precautions: Avoid contact with skin and eyes.
Avoid inhalation of vapour or mist.
Keep away from sources of ignition – No smoking.
Take measures to prevent the build up of electrostatic charge.
Enviromental Precautions: Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Exposure Controls | Personal Protection
Derived No Effect Level (DNEL)
Workers | Application Area | Exposure Routes | Health Effect | Value
No Data Available
Consumers | Application Area | Exposure Routes | Health Effect | Value
No Data Available
Predicted No Effect Concentration (PNEC)
No Data Available
Engineering Controls: Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Eye/Face Protection: Face shield and safety glasses. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin Protection: Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching gloves outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU
Directive 89/686/EEC and the standard EN 374 derived from it.
Splash contact –
Material: Fluorinated rubber. Minimum layer thickness: 0,7 mm
Break through time: 54 min. Material tested: Vitoject®
Data source: KCL GmbH, D-36124. Test method: EN374.
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Body Protection: Complete suit protecting against chemicals. Flame retardant anti-static protective clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory Protection: Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multipurpose combination OV/AG (US) or type AXBEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Physical and Chemical Properties
Appearance: Clear, volatile, mobile liquid
Odour: Sweet, Ether-like
Odour Threshold: No Data Available
pH: No Data Available
Melting Point: Melting point/range: -116 °C
Boiling Point: 34,6 °C at 1.013 hPa
Flash Point: -40 °C (closed cup)
Evaporation: No Data Available
Flammability: No Data Available
Upper/Lower Flammability or Explosive Limits: Upper explosion limit: 36% (V),
Lower explosion limit: 1,7 % (V).
Vapour pressure: 189 hPa at 0 °C,
389 hPa at 10 °C,
563 hPa at 20 °C,
863 hPa at 30 °C,
1.228 hPa at 40 °C,
2.311 hPa at 60 °C.
Vapour density: 2,56 – (Air = 1.0)
Relative density: 0,71 g/cm3 at 20 °C
Water solubility: Miscible
Partition Coefficien: log Pow: 1,1
Auto-ignition Temperature: 175 °C at 1.013,25 hPa
Decomposition Temperature: No Data Available
Viscosity: No Data Available
Explosive properties: No Data Available
Oxidizing properties: No Data Available
Other Safety Info: Relative vapour density: 2,56 – (Air = 1.0)
Stability and Reactivity
Reactivity: No Data Available
Chemical Stability: Stable under recommended storage conditions.
Possibility of hazardous reactions: No Data Available
Conditions to Avoid: Heat, flames and sparks.
Incompatible Materials: Oxidizing agents, Strong acids
Hazardous Decomposition Products: Hazardous decomposition products formed under fire conditions – Carbon Oxides
Acute Toxicity: LD50 Oral – Rat – 1.211 mg/kg – (OECD Test Guideline 401).
LC50 Inhalation – Mouse – 4h – 97,5mg/l
LD50 Dermal – Rabbit – male – > 20.000 mg/kg (OECD Test Guideline 402).
Skin Corrosion/Irritation: Rabbit –
Result: No skin irritation – 4h
(OECD Test Guideline 404) Dermatitus.
Serious Eye damage | Eye Irritation: Rabbit –
Result: No eye irritation
(OECD Test Guideline 405)
Cell Mutagenicity: Micronucleus test:
Human lymphocytes – Result: negative.
In vitro mammalian cell gene mutation test:
Mouse lymphoma test – Result: negative – OECD Test Guideline 474
Mouse – male and female
Carcinogenicity: IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity: No Data Available
Specific Target Organ Toxicity – Single Exposure: Central nervous system -May cause drowsiness or dizziness.
Acute oral toxicity – Risk of aspiration upon vomiting, Aspiration may cause pulmonary oedema and pneumonitis.
Acute inhalation toxicity – Mucosal irritations
Specific Target Organ Toxicity – Repeated Exposure: No Data Available
Aspiration Hazard: No Data Available
Ecological Toxicity: Toxicity to fish:
LC50 – Leuciscus idus (Golden orfe) – 2.840 mg/l – 48 h – Remarks: (ECOTOX Database).
Toxicity to daphnia and other aquatic invertebrates:
EC50 – Daphnia magna (Water flea) – 1.380 mg/l – 48 h – Remarks: (IUCLID).
Toxicity to algae:
Static test ErC50 – Desmodesmus subspicatus (green algae) – > 100 – mg/l – 72 h – (OECD Test Guideline 201).
Toxicity to bacteria:
Static test EC50 – activated sludge – 21.000 mg/l – 3 h – (OECD Test Guideline 209).
Static test NOEC – activated sludge – 42 mg/l – 3 h – (OECD Test Guideline 209).
Ecological Persistence and degradability: Not readily biodegradable.
Bioaccumulative Potential: No bioaccumulation is to be expected (log Pow <= 4).
Mobility in Soil: No Data Available
Results of PBT and vPvB Assessment: This substance contains no components considered to be either persistent, bio-accumulative and toxic (PBT), or very persistent and very bio-accumulative (vPvB) at levels of 0.1% or higher.
Other Adverse Effect: No Data Available
Waste Treatment Methods: Product –
Offer surplus and non-recyclable solutions to a licensed disposal company. Waste material must be disposed of in accordance with the Directive on waste 2008/98/EC as well as other national and local regulations. Leave chemicals in original containers. No mixing with other waste. Handle uncleaned containers like the product itself.
Contaminated packaging – Dispose of as unused product.
UN Number: ADR/RID: 1155
UN Shipping Hazard: ADR/RID: DIETHYL ETHER
IMDG: DIETHYL ETHER
IATA: Diethyl Ether
Transport Hazard Class: ADR/RID: 3
Packaging Group: ADR/RID: I
Enviromental Hazards: ADR/RID: no
IMDG Marine pollutant: no
Special Precautions: No data available
Safety, Health and environmental regulations: This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
Chemical Safety Assessment: For this product a chemical safety assessment was not carried out.
Additional Info: RTECS: KI5775000
Inhalation may provoke the following symptoms:
Cough, Chest pain, Difficulty in breathing, Dizziness, Drowsiness.
Contact with eyes can cause, Redness, Provokes tears, Blurred vision.
Prolonged or repeated exposure to skin causes defatting and dermatitis.
Liver – Ingestion may provoke the following symptoms: Irregularities – Based on Human Evidence
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
The information stated above is considered to be correct, but does not claim to be inclusive and shall only be used as a guideline. The information provided by this document is confirmed by our continuous updating of knowledge and adheres to the products appropriate safety precautions. It does not represent any guarantee of the product’s
properties. RLS Chemicals and its Associates shall not be held accountable for any damage’s consequent of handling the above product.