Toluene AR – Identification of Product
Chemical Code: CHE-T5
Chemical Name: Toluene
Chemical Grade: AR
Chemical Formula: C₇H₈
Chemical Weight: 92,14 g/mol
CAS No: 108-88-3
Chemical Synonyms: Toluol
Toluene AR – Hazards Identification
REACH No: 01-2119471310-51-XXXX
Signal Word: Danger
Supplemental Hazard Information:
Additional Hazard Information: This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Toluene AR – Hazards statements
H225 – Highly flammable liquid and vapour.
H304 – May be fatal if swallowed and enters airways.
H315 – Causes skin irritation.
H336 – May cause drowsiness or dizziness.
H361d – Suspected of damaging the unborn child.
H373 – May cause damage to organs through prolonged or repeated exposure.
Toluene AR – Precautionary statements
P210 – Keep away from heat/sparks/open flames/hot surfaces. No smoking.
P261 – Avoid breathing vapours.
P281 – Use personal protective equipment as required.
P301 + P310 – IF SWALLOWED: Immediately call a POISON CENTER/doctor.
P331 – Do NOT induce vomiting
Toluene AR – Composition of Chemical
Chemical Formula: C₇H₈
EC No 1272/2008: 01-2119471310-51-XXXX
Toluene AR – First Aid Measures
General Advice: Consult a physician. Show this safety data sheet to the doctor in attendance
If: Inhaled: If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician
If: Skin Contact: Wash off with soap and plenty of water. Consult a physician.
If: Eye Contac: Flush eyes with water as a precaution.
If: Swallowed: Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Important Symptoms: The most important known symptoms and effects are described in the labeling section
Immediate Medical Attention: No Data Available
Firefighting Measures
Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide
Hazards Arising: No Data Available
Advice for Firefighters: Wear self-contained breathing apparatus for firefighting if necessary.
Info for Firefighting: Use water spray to cool unopened containers
Accidental Release Measures
Personal Precautions: Use personal protective equipment.
Avoid breathing vapours, mist or gas.
Ensure adequate ventilation.
Remove all sources of ignition.
Evacuate personnel to safe areas.
Beware of vapours accumulating to form explosive concentrations.
Vapours can accumulate in low areas.
Enviromental Precautions: Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.
Method for Containment: Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations
Handling and Storage
Personal Precautions: Avoid contact with skin and eyes.
Avoid inhalation of vapour or mist.
Keep away from sources of ignition – No smoking.
Take measures to prevent the build up of electrostatic charge.
Enviromental Precautions: Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Exposure Controls | Personal Protection
Derived No Effect Level (DNEL)
Workers | Application Area | Exposure Routes | Health Effect | Value
Workers – Inhalation – Acute systemic effects – 384 mg/m3
Workers – Inhalation – Acute local effects – 384 mg/m3
Workers – Skin contact – Long-term systemic effects – 384mg/kg BW/d
Workers – Inhalation – Long-term systemic effects – 192 mg/m3
Workers – Inhalation – Long-term local effects – 192 mg/m3
Consumers | Application Area | Exposure Routes | Health Effect | Value
Consumers – Inhalation – Acute systemic effects – 226 mg/m3
Consumers – Inhalation – Acute local effects – 226 mg/m3
Consumers – Skin contact – Long-term systemic effects – 226mg/kg BW/d
Consumers – Inhalation – Long-term systemic effects – 56,5 mg/m3
Consumers – Ingestion – Long-term systemic effects – 8,13mg/kg BW/d
Predicted No Effect Concentration (PNEC)
Soil – 2,89 mg/kg
Marine water – 0,68 mg/l
Fresh water – 0,68 mg/l
Marine sediment – 16,39 mg/kg
Fresh water sediment – 16,39 mg/kg
Sewage treatment plant – 13,61 mg/l
Aquatic intermittent release – 0,68 mg/l
Engineering Controls: Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Eye/Face Protection: Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin Protection: Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove’s outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Full contact – Material: Fluorinated rubber. Minimum layer thickness: 0,7 mm
Break through time: 480 min. Material tested: Vitoject®
Splash contact – Material: Fluorinated rubber. Minimum layer thickness: 0,7 mm
Break through time: 480 min. Material tested: Vitoject®
Data source: KCL GmbH, D-36124. Test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374,contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Body Protection: Complete suit protecting against chemicals. Flame retardant anti-static protective clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace Respiratory Protection: Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multipurpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Physical and Chemical Properties
Appearance: Clear, Colourless liquid
Odour: Aromatic
Odour Threshold: No Data Available
pH: No Data Available
Melting Point: Melting point/range: -93 °C
Boiling Point: 110.1 – 111.5 °C
Flash Point: 4,0 °C – closed cup
Evaporation: No Data Available
Flammability: No data available
Upper/Lower Flammability or Explosive Limits: Upper explosion limit: 7 %(V), Lower explosion limit: 1,2 %(V)
Vapour pressure: 29,1 hPa at 20,0 °C
Vapour density: No Data Available
Relative density: 0,865 g/mL at 25 °C
Water solubility: 0,5 g/l at 15 °C
Partition Coefficien: No Data Available
Auto-ignition Temperature: 535,0 °C
Decomposition Temperature: No Data Available
Viscosity: No Data Available
Explosive properties: No Data Available
Oxidizing properties: No Data Available
Other Safety Info: No Data Available
Stability and Reactivity
Reactivity: No Data Available
Chemical Stability: Stable under recommended storage conditions
Possibility of hazardous reactions: No Data Available
Conditions to Avoid: Heat, flames and sparks.
Extremes of temperature and direct sunlight
Incompatible Materials: Strong oxidizing agents
Hazardous Decomposition Products: Carbon Oxides
Toxicological Information
Acute Toxicity: LD50 Oral – Rat – > 5.580 mg/kg
LC50 Inhalation – Rat – 4 h – 12.500 – 28.800 mg/m3
LD50 Dermal – Rabbit – 12.196 mg/kg
Skin Corrosion/Irritation: Rabbit
Result: Skin irritation – 24 h
Serious Eye damage | Eye Irritation: Rabbit
Result: No eye irritation
(OECD Test Guideline 405)
Cell Mutagenicity: Rat
Liver
DNA damage
Carcinogenicity: IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity: Damage to fetus possible
Suspected human reproductive toxicant
Reproductive toxicity – Rat – Inhalation
Paternal Effects: Spermatogenesis (including genetic material, sperm morphology,motility, and count).
Experiments have shown reproductive toxicity effects in male and female laboratory animals.
Developmental Toxicity – Rat – Oral
Effects on Embryo or Fetus: Fetotoxicity (except death, e.g., stunted fetus).
Specific Target Organ Toxicity – Single Exposure: No Data Available
Specific Target Organ Toxicity – Repeated Exposure: No Data Available
Aspiration Hazard: No Data Available
Ecological Information
Ecological Toxicity: Toxicity to fish:
LC50 – Oncorhynchus mykiss (rainbow trout) – 7,63 mg/l – 96 h
NOEC – Pimephales promelas (fathead minnow) – 5,44 mg/l – 7 d
Toxicity to daphnia and other aquatic invertebrates:
EC50 – Daphnia magna (Water flea) – 8,00 mg/l – 24 h
Immobilization EC50 – Daphnia magna (Water flea) – 6 mg/l – 48 h
Toxicity to algae:
EC50 – Chlorella vulgaris (Fresh water algae) – 245,00 mg/l – 24 h
EC50 – Pseudokirchneriella subcapitata (green algae) – 10,00 mg/l – 24 h
Ecological Persistence and degradability: Biodegradability Result: – Readily biodegradable
Bioaccumulative Potential: Bioaccumulation Leuciscus idus (Golden orfe) – 3 d – 0,05 mg/l
Bioconcentration factor (BCF): 90
Mobility in Soil: No Data Available
Results of PBT and vPvB Assessment: This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other Adverse Effect: Toxic to aquatic life.
Disposal Considerations
Waste Treatment Methods: Product –
Burn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting as this material is highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging – Dispose of as unused product
Transport Information
UN Number: ADR/RID: 1294
IMDG: 1294
IATA: 1294
UN Shipping Hazard: ADR/RID: TOLUENE
IMDG: TOLUENE
IATA: Toluene
Transport Hazard Class: ADR/RID: 3
IMDG: 3
IATA: 3
Packaging Group: ADR/RID: II
IMDG: II
IATA: II
Enviromental Hazards: ADR/RID: no
IMDG Marine pollutant: no
IATA: no
Special Precautions: No Data Available
Regulatory Information
Safety, Health and environmental regulations: REACH – Restrictions on the manufacture, placing on the market and use of certain dangerous substances, preparations and articles: Toluene
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
Chemical Safety Assessment: A Chemical Safety Assessment has been carried out for this substance.
Additional Info: RTECS: XS5250000
Lung irritation, Chest pain, Pulmonary edema.
Inhalation studies on toluene have demonstrated the development of inflammatory and ulcerous lesions of the penis, prepuce, and scrotum in animals.
Central nervous system
Disclaimer
The information stated above is considered to be correct, but does not claim to be inclusive and shall only be used as a guideline. The information provided by this document is confirmed by our continuous updating of knowledge and adheres to the products appropriate safety precautions. It does not represent any guarantee of the product’s properties. RLS Chemicals and its Associates shall not be held accountable for any damage’s consequent of handling the above product.
