2-Propanol 99.8% HPLC & Spectroscopy

Details of the supplier of the safety data sheet

1 2-Propanol 99.8% HPLC Identification
2 Hazard(s) identification
· Classification of the substance or mixture
Flam. Liq. 2 H225 Highly flammable liquid and vapor.
Eye Irrit. 2A H319 Causes serious eye irritation. STOT SE 3 H336 May cause drowsiness or dizziness.
· Label elements
·
GHS label elements The product is classified and labeled according to the Globally Harmonized System (GHS).

Signal word Danger
· Hazard-determining components of labeling:
Isopropanol
· Hazard statements
Highly flammable liquid and vapor. Causes serious eye irritation.
May cause drowsiness or dizziness.
· Precautionary statements
Keep away from heat/sparks/open flames/hot surfaces. – No smoking. Ground/bond container and receiving equipment.

2-Propanol 99.8% HPLC Safety Data Sheet
Chemical characterization: Mixtures
Description: Mixture of the substances listed below with nonhazardous additions.
3 Composition/information on ingredients
· Dangerous components:
CAS: 67-63-0
Isopropanol
< = 99.8%
4 First-aid measures
· Description of first aid measures
·
After inhalation: Supply fresh air; consult doctor in case of complaints.
·
After skin contact: Generally the product does not irritate the skin.
Other hazards
Results of PBT and vPvB assessment
PBT: Not applicable.
vPvB: Not applicable.
Health = 2
Fire = 3
Reactivity = 0
REACTIVITY 0
· HMIS-ratings (scale 0 – 4)
HEALTH 2
FIRE 3
Health = 2
Fire = 3
Reactivity = 0
3
2 0

Use explosion-proof electrical/ventilating/lighting/equipment. Use only non-sparking tools.
Take precautionary measures against static discharge. Avoid breathing dust/fume/gas/mist/vapors/spray Wash thoroughly after handling.
Use only outdoors or in a well-ventilated area.
Wear protective gloves/protective clothing/eye protection/face protection.
If on skin (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove person to fresh air and keep comfortable for breathing.
If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Call a poison center/doctor if you feel unwell.
If eye irritation persists: Get medical advice/attention.
In case of fire: Use for extinction: CO2, powder or water spray. Store in a well-ventilated place. Keep container tightly closed. Store in a well-ventilated place. Keep cool.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

2-Propanol 99.8% HPLC Classification system:
NFPA ratings (scale 0 – 4)

2-Propanol 99.8% HPLC Extinguishing media

Suitable extinguishing agents:
CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
Special hazards arising from the substance or mixture No further relevant information available.
Advice for firefighters
Protective equipment: No special measures required.
Personal precautions, protective equipment and emergency procedures
Wear protective equipment. Keep unprotected persons away.
Environmental precautions:
Dilute with plenty of water.
Do not allow to enter sewers/ surface or ground water.
Methods and material for containment and cleaning up:
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust). Ensure adequate ventilation.
Reference to other sections
See Section 7 for information on safe handling.
See Section 8 for information on personal protection equipment. See Section 13 for disposal information.
Protective Action Criteria for Chemicals
5 Fire-fighting measures
6 Accidental release measures
· PAC-1:
CAS: 67-63-0
Isopropanol
400 ppm
· PAC-2:
CAS: 67-63-0
Isopropanol
2000* ppm
· PAC-3:
CAS: 67-63-0
Isopropanol
12000** ppm
7 2-Propanol 99.8% HPLC Handling and storage
· Handling:
·
Precautions for safe handling No special precautions are necessary if used correctly.
· Information about protection against explosions and fires:
Keep ignition sources away – Do not smoke. Protect against electrostatic charges.

After eye contact:
Rinse opened eye for several minutes under running water. If symptoms persist, consult a doctor.

After swallowing: If symptoms persist consult doctor.

2-Propanol 99.8% Information for doctor:

Most important symptoms and effects, both acute and delayed No further relevant information available.

Indication of any immediate medical attention and special treatment needed
No further relevant information available.

8 2-Propanol 99.8% HPLC Exposure controls/personal protection

Additional information about design of technical systems: No further data; see item 7.
· Control parameters
· Components with limit values that require monitoring at the workplace:
CAS: 67-63-0 Isopropanol
PEL
REL TLV
Long-term value: 980 mg/m³, 400 ppm
Short-term value: 1225 mg/m³, 500 ppm
Long-term value: 980 mg/m³, 400 ppm
Short-term value: 984 mg/m³, 400 ppm
Long-term value: 492 mg/m³, 200 ppm BEI
· Ingredients with biological limit values:
CAS: 67-63-0 Isopropanol
BEI
40 mg/L
LD50 Intraperitoneal: urine
Time: end of shift at end of workweek LD50: Acetone (background, nonspecific)
·
Additional information: The lists that were valid during the creation were used as basis.
·
Exposure controls
·
Personal protective equipment:
·
General protective and hygienic measures:
Keep away from foodstuffs, beverages and feed. Immediately remove all soiled and contaminated clothing. Wash hands before breaks and at the end of work.
Avoid contact with the eyes.
Avoid contact with the eyes and skin.
·
Breathing equipment: Not required.
· Protection of hands:
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/ the chemical mixture.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
· Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance of the glove material can not be calculated in advance and has therefore to be checked prior to the application.
· Penetration time of glove material
The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.

Conditions for safe storage, including any incompatibilities
·
Storage:
·
Requirements to be met by storerooms and receptacles: Store in a cool location.
·
Information about storage in one common storage facility: Not required.
·
Further information about storage conditions:
Keep receptacle tightly sealed.
Store in cool, dry conditions in well sealed receptacles.
·
Specific end use(s) No further relevant information available.

9 2-Propanol 99.8% HPLC Physical and chemical properties
·
Information on basic physical and chemical properties
·
General Information
·
Appearance:
Form: Liquid
Color: Clear Colourless
·
Odor: Alcohol
·
Odor threshold: Not determined.
· pH-value:
Not determined.
· Change in condition
Melting point/Melting range: Boiling point/Boiling range:
Undetermined. 82 °C (179.6 °F)
· Flash point:
13 °C (55.4 °F)
· Flammability (solid, gaseous):
Not applicable.
· Ignition temperature:
425 °C (797 °F)
· Decomposition temperature:
Not determined.
· Auto igniting:
Product is not selfigniting.
· Danger of explosion:
Product is not explosive. However, formation of explosive air/vapor mixtures are possible.
· Explosion limits: Lower:
Upper:
2 Vol %
12 Vol %
· Vapor pressure at 20 °C (68 °F):
43 hPa (32.3 mm Hg)
·
Density at 25 °C:
·
Relative density
·
Vapor density
·
Evaporation rate
0.785 g/cm³ (6.7733 lbs/gal) Not determined.
Not determined. Not determined.
· Solubility in / Miscibility with Water:
Fully miscible.
· Partition coefficient (n-octanol/water): Not determined.
· Viscosity: Dynamic: Kinematic:
Not determined. Not determined.
· Solvent content: Organic solvents:
·
Eye protection:
·
Body protection: Protective work clothing

Reactivity No further relevant information available.
Chemical stability
Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
Possibility of hazardous reactions No dangerous reactions known.
Conditions to avoid No further relevant information available.
Incompatible materials: No further relevant information available.
Hazardous decomposition products: No dangerous decomposition products known.
Information on toxicological effects
Acute toxicity:
Primary irritant effect:
on the skin: No irritant effect.
on the eye: Irritating effect.
Sensitization: No sensitizing effects known.
Additional toxicological information:
The product shows the following dangers according to internally approved calculation methods for preparations: Irritant
Carcinogenic categories
· Other information No further relevant information available.
10 Stability and reactivity
11 Toxicological information
· LD/LC50 values that are relevant for classification:
ATE (Acute Toxicity Estimate)
Inhalative
LC50/4 h
34.2 mg/l (rat)
CAS: 67-63-0 Isopropanol
Oral
LD50
5,045 mg/kg (rat)
Dermal
LD50
12,800 mg/kg (rabbit)
Inhalative
LC50/4 h
30 mg/l (rat)
· IARC (International Agency for Research on Cancer)
CAS: 67-63-0
Isopropanol
3
· NTP (National Toxicology Program)
None of the ingredients is listed.
· OSHA-Ca (Occupational Safety & Health Administration)
None of the ingredients is listed.

Toxicity
Aquatic toxicity: No further relevant information available.
Persistence and degradability No further relevant information available.
Behavior in environmental systems:
Bioaccumulative potential No further relevant information available.
Mobility in soil No further relevant information available.
Additional ecological information:
General notes:
Water hazard class 1 (Self-assessment): slightly hazardous for water
Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system.
Results of PBT and vPvB assessment
PBT: Not applicable.
vPvB: Not applicable.
Other adverse effects No further relevant information available.
Waste treatment methods
Recommendation:
Must not be disposed of together with household garbage. Do not allow product to reach sewage system.
Uncleaned packagings:
Recommendation: Disposal must be made according to official regulations.
Recommended cleansing agent: Water, if necessary with cleansing agents.
(Contd. of page 6)
12 Ecological information
13 Disposal considerations
14 Transport information
·
UN-Number
·
DOT, IMDG, IATA
UN1219
·
UN proper shipping name
·
DOT, IMDG, IATA
Isopropanol solution
· Transport hazard class(es)
· DOT
· Class
3 Flammable liquids
· Label
3
·
IMDG, IATA
·
Class
3 Flammable liquids
Safety, health and environmental regulations/legislation specific for the substance or mixture
Sara
· Proposition 65
· Label 3
·
Packing group
·
DOT, IMDG, IATA II
· Environmental hazards: Not applicable.
·
Special precautions for user Warning: Flammable liquids
·
Danger code (Kemler): 33
·
Stowage Category B
· Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code Not applicable.
·
Transport/Additional information:
·
DOT
·
Quantity limitations On passenger aircraft/rail: 5 L On cargo aircraft only: 60 L
·
IMDG
·
Limited quantities (LQ) 1L
·
Excepted quantities (EQ) Code: E2
Maximum net quantity per inner packaging: 30 ml Maximum net quantity per outer packaging: 500 ml
· UN “Model Regulation”: UN 1219 ISOPROPANOL SOLUTION, 3, II
15 Regulatory information
· Section 355 (extremely hazardous substances):
None of the ingredients is listed.
· Section 313 (Specific toxic chemical listings):
CAS: 67-63-0
Isopropanol
· TSCA (Toxic Substances Control Act):
Isopropanol
Water
· Chemicals known to cause cancer:
None of the ingredients is listed.
· Chemicals known to cause reproductive toxicity for females:
None of the ingredients is listed.
· Chemicals known to cause reproductive toxicity for males:
None of the ingredients is listed.
· Chemicals known to cause developmental toxicity:
None of the ingredients is listed.
Page 9/10
Safety Data Sheet
acc. to OSHA HCS
Printing date 22/11/2024 Reviewed on 22/11/2024
TRADE NAME: 2-PROPANOL 99.8% FOR HPLC & SPECTROSCOPY
(Contd. of page 8)
46.0
This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship.
· Department issuing SDS: Environment protection department.
(Contd. on page 10)
· Carcinogenic categories
· EPA (Environmental Protection Agency)
None of the ingredients is listed.
· TLV (Threshold Limit Value established by ACGIH)
CAS: 67-63-0
Isopropanol
A4
· NIOSH-Ca (National Institute for Occupational Safety and Health)
None of the ingredients is listed.
·
GHS label elements The product is classified and labeled according to the Globally Harmonized System (GHS).
·
Hazard pictograms
·
Signal word Danger
· Hazard-determining components of labeling:
Isopropanol
· Hazard statements
Highly flammable liquid and vapor. Causes serious eye irritation.
May cause drowsiness or dizziness.
· Precautionary statements
Keep away from heat/sparks/open flames/hot surfaces. – No smoking. Ground/bond container and receiving equipment.
Use explosion-proof electrical/ventilating/lighting/equipment. Use only non-sparking tools.
Take precautionary measures against static discharge. Avoid breathing dust/fume/gas/mist/vapors/spray Wash thoroughly after handling.
Use only outdoors or in a well-ventilated area.
Wear protective gloves/protective clothing/eye protection/face protection.
If on skin (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove person to fresh air and keep comfortable for breathing.
If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Call a poison center/doctor if you feel unwell.
If eye irritation persists: Get medical advice/attention.
In case of fire: Use for extinction: CO2, powder or water spray. Store in a well-ventilated place. Keep container tightly closed. Store in a well-ventilated place. Keep cool.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
·
Chemical safety assessment: A Chemical Safety Assessment has not been carried out.
16 Other information

Date of preparation / last revision
Creation date for SDS 08/11/2023
Review SDS for accuracy. 22/11/2024 STN