Acetic Acid 99.8% HPLC Product identifier
Trade name: ACETIC ACID 99.8% FOR HPLC & SPECTROSCOPY

Classification of the substance or mixture
Flammable Liquids 3 H226 Flammable liquid and vapor.
Skin Corrosion 1A H314 Causes severe skin burns and eye damage. Eye Damage 1 H318 Causes serious eye damage.
Sensitization – Skin 1 H317 May cause an allergic skin reaction.
· Label elements
·
GHS label elements The product is classified and labeled according to the Globally Harmonized System (GHS).

Signal word Danger
· Hazard-determining components of labeling:
Acetic Acid, Glacial
Hazard statements
Flammable liquid and vapor. 2 Hazard(s) identification

1 Acetic Acid 99.8% HPLC Identification
3 Composition/information on ingredients
Chemical characterization: Mixtures
Description: Mixture of the substances listed below with nonhazardous additions.
· Dangerous components:
CAS: 64-19-7
Acetic Acid, Glacial
99.8% Min
Causes severe skin burns and eye damage.
May cause an allergic skin reaction.

Acetic Acid 99.8% HPLC Precautionary statements
Keep away from heat/sparks/open flames/hot surfaces. – No smoking. Keep container tightly closed.
Ground/bond container and receiving equipment.
Use explosion-proof electrical/ventilating/lighting/equipment. Use only non-sparking tools.
Take precautionary measures against static discharge. Do not breathe dusts or mists.
Wash thoroughly after handling.
Contaminated work clothing must not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. If swallowed: Rinse mouth. Do NOT induce vomiting.
If on skin (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove person to fresh air and keep comfortable for breathing.
If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Immediately call a poison center/doctor. Specific treatment (see on this label).
If skin irritation or rash occurs: Get medical advice/attention. Wash contaminated clothing before reuse.
In case of fire: Use CO2, powder or water spray to extinguish. Store in a well-ventilated place. Keep cool.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
Classification system:
NFPA ratings (scale 0 – 4)
Other hazards
Results of PBT and vPvB assessment
PBT: Not applicable.
vPvB: Not applicable.

Acetic Acid 99.8% HPLC Extinguishing media
Suitable extinguishing agents:
CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
Special hazards arising from the substance or mixture
During heating or in case of fire poisonous gases are produced.
Advice for firefighters
Protective equipment: Mouth respiratory protective device.
Personal precautions, protective equipment and emergency procedures
Mount respiratory protective device.
Wear protective equipment. Keep unprotected persons away.
Environmental precautions:
Do not allow product to reach sewage system or any water course.
Inform respective authorities in case of seepage into water course or sewage system. Dilute with plenty of water.
Do not allow to enter sewers/ surface or ground water.
Methods and material for containment and cleaning up:
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust). Use neutralizing agent.
Dispose contaminated material as waste according to section 13. Ensure adequate ventilation.
Reference to other sections
See Section 7 for information on safe handling.
See Section 8 for information on personal protection equipment. See Section 13 for disposal information.
*
5 Acetic Acid 99.8% HPLC Fire-fighting measures
*
Description of first aid measures
General information: Immediately remove any clothing soiled by the product.
After inhalation:
Supply fresh air and to be sure call for a doctor.
In case of unconsciousness place patient stably in side position for transportation.
After skin contact: Immediately wash with water and soap and rinse thoroughly.
After eye contact: Rinse opened eye for several minutes under running water. Then consult a doctor.
After swallowing: Drink copious amounts of water and provide fresh air. Immediately call a doctor.
Information for doctor:
Most important symptoms and effects, both acute and delayed No further relevant information available.
Indication of any immediate medical attention and special treatment needed
No further relevant information available. 4 First-aid measures

6 Acetic Acid 99.8% HPLC Accidental release measures

· Protective Action Criteria for Chemicals
Handling:
Precautions for safe handling
Ensure good ventilation/exhaustion at the workplace. Prevent formation of aerosols.
Information about protection against explosions and fires:
Keep ignition sources away – Do not smoke. Protect against electrostatic charges.
Keep respiratory protective device available.
Conditions for safe storage, including any incompatibilities
Storage:
Requirements to be met by storerooms and receptacles: No special requirements.
Information about storage in one common storage facility: Not required.
Further information about storage conditions: Keep receptacle tightly sealed.
Specific end use(s) No further relevant information available.
Additional information about design of technical systems: No further data; see section 7.
Control parameters
Additional information: The lists that were valid during the creation were used as basis.
Exposure controls
Personal protective equipment:
General protective and hygienic measures:
Keep away from foodstuffs, beverages and feed. Immediately remove all soiled and contaminated clothing. Wash hands before breaks and at the end of work.
Avoid contact with the eyes.
Avoid contact with the eyes and skin.
· PAC-1:
CAS: 64-19-7
Acetic Acid, Glacial
5 ppm
· PAC-2:
CAS: 64-19-7
Acetic Acid, Glacial
35 ppm
· PAC-3:
CAS: 64-19-7
Acetic Acid, Glacial
250 ppm
7 Acetic Acid 99.8% HPLC Handling and storage
*
· Components with limit values that require monitoring at the workplace:
CAS: 64-19-7 Acetic Acid, Glacial
PEL
REL
TLV
Long-term value: 25 mg/m³, 10 ppm
Short-term value: 37 mg/m³, 15 ppm
Long-term value: 25 mg/m³, 10 ppm Short-term value: 15 ppm
Long-term value: 10 ppm 8 Exposure controls/personal protection

Information on basic physical and chemical properties
·
Acetic Acid 99.8% HPLC General Information
·
Appearance:
Form: Liquid
Color: Colorless
·
Odor: Strong Vinegar
·
Odor threshold: Not determined.
· pH-value at 20 °C (68 °F):
<2
· Change in condition
Melting point/Melting range: Boiling point/Boiling range:
Undetermined. 100-118°C
· Flash point:
40 °C (104 °F)
· Flammability (solid, gaseous):
Flammable.
· Auto igniting:
485 °C (905 °F)
· Decomposition temperature:
Not determined.
· Ignition temperature:
Product is not selfigniting.
· Danger of explosion:
Product is not explosive. However, formation of explosive air/vapor mixtures are possible.
·
Breathing equipment:
In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use respiratory protective device that is independent of circulating air.
·
Protection of hands:
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/ the chemical mixture.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
·
Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance of the glove material can not be calculated in advance and has therefore to be checked prior to the application.
·
Penetration time of glove material
The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.
·
Eye protection:
·
Body protection: Protective work clothing 9 Physical and chemical properties

Reactivity No further relevant information available.
Acetic Acid 99.8% HPLC Chemical stability
Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
Possibility of hazardous reactions No dangerous reactions known.
Conditions to avoid No further relevant information available.
Incompatible materials: No further relevant information available.
Hazardous decomposition products: No dangerous decomposition products known.
Information on toxicological effects
Acute toxicity:
Primary irritant effect:
on the skin: Strong caustic effect on skin and mucous membranes.
on the eye:
Strong caustic effect.
Strong irritant with the danger of severe eye injury.
Sensitization: Sensitization possible through skin contact.
· Explosion limits: Lower:
Upper:
4 Vol %
17 Vol %
· Vapor pressure at 20 °C (68 °F):
23 hPa (17.3 mm Hg)
·
Density at 20 °C (68 °F):
·
Relative density
·
Vapor density
·
Evaporation rate
1.05 g/cm³
Not determined.
Not determined. Not determined.
· Solubility in / Miscibility with Water:
Fully miscible.
· Partition coefficient (n-octanol/water): Not determined.
· Viscosity: Dynamic: Kinematic:
Not determined. Not determined.
· Solvent content: Organic solvents: Water:
VOC content:
Not applicable.
0.2% Max
Not applicable.
Solids content:
0.0 %
· Other information
No further relevant information available.
10 Stability and reactivity
*
· LD/LC50 values that are relevant for classification:
ATE (Acute Toxicity Estimate)
Dermal
LD50
2,070 mg/kg (rabbit) 11 Toxicological information
Page 7/10
Safety Data Sheet
acc. to OSHA HCS
Printing date 20/01/2025 Reviewed on 20/01/2025
TRADE NAME: ACETIC ACID 99.8% FOR HPLC & SPECTROSCOPY

Additional toxicological information:
The product shows the following dangers according to internally approved calculation methods for preparations: Corrosive
Irritant
Swallowing will lead to a strong caustic effect on mouth and throat and to the danger of perforation of esophagus and stomach.
Carcinogenic categories
Toxicity
Aquatic toxicity: No further relevant information available.
Persistence and degradability No further relevant information available.
Behavior in environmental systems:
Bioaccumulative potential No further relevant information available.
Mobility in soil No further relevant information available.
Additional ecological information:
General notes:
Water hazard class 1 (Self-assessment): slightly hazardous for water
Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system. Must not reach bodies of water or drainage ditch undiluted or unneutralized.
Rinse off of bigger amounts into drains or the aquatic environment may lead to decreased pH-values. A low pH- value harms aquatic organisms. In the dilution of the use-level the pH-value is considerably increased, so that after the use of the product the aqueous waste, emptied into drains, is only low water-dangerous.
Results of PBT and vPvB assessment
PBT: Not applicable.
vPvB: Not applicable.
Other adverse effects No further relevant information available.
Waste treatment methods
Recommendation:
Must not be disposed of together with household garbage. Do not allow product to reach sewage system.
Uncleaned packagings:
Recommendation: Disposal must be made according to official regulations.
Recommended cleansing agent: Water, if necessary with cleansing agents.
· IARC (International Agency for Research on Cancer)
None of the ingredients is listed.
· NTP (National Toxicology Program)
None of the ingredients is listed.
· OSHA-Ca (Occupational Safety & Health Administration)
None of the ingredients is listed.
12 Ecological information
13 Disposal considerations

UN-Number
·
DOT, IMDG, IATA UN2790
·
UN proper shipping name
·
DOT Acetic acid solution
·
IMDG, IATA ACETIC ACID SOLUTION
·
Transport hazard class(es)
·
DOT
·
Class 8 Corrosive substances
·
Label 8
·
IMDG, IATA
·
Class 8 Corrosive substances
·
Label 8
·
Packing group
·
DOT, IMDG, IATA II
·
Environmental hazards:
·
Marine pollutant: No
·
Special precautions for user Warning: Corrosive substances
·
Hazard identification number (Kemler code): 80
·
EMS Number: F-A,S-B
·
Segregation groups (SGG1) Acids
·
Stowage Category A
· Transport in bulk according to Annex II of
MARPOL73/78 and the IBC Code Not applicable.
·
Transport/Additional information:
·
DOT
·
Quantity limitations On passenger aircraft/rail: 1 L On cargo aircraft only: 30 L
·
IMDG
·
Limited quantities (LQ) 1L
·
Excepted quantities (EQ) Code: E2
Maximum net quantity per inner packaging: 30 ml Maximum net quantity per outer packaging: 500 ml
· UN “Model Regulation”: UN 2790 ACETIC ACID SOLUTION, 8, II 14 Transport information

· Safety, health and environmental regulations/legislation specific for the substance or mixture
No further relevant information available.
·
Sara
· Section 355 (extremely hazardous substances):
None of the ingredients is listed.
· Section 313 (Specific toxic chemical listings):
None of the ingredients is listed.
· TSCA (Toxic Substances Control Act):
Acetic Acid, Glacial
ACTIVE
Water
ACTIVE
· Hazardous Air Pollutants
None of the ingredients is listed.
·
Proposition 65
· Chemicals known to cause cancer:
None of the ingredients is listed.
· Chemicals known to cause reproductive toxicity for females:
None of the ingredients is listed.
· Chemicals known to cause reproductive toxicity for males:
None of the ingredients is listed.
· Chemicals known to cause developmental toxicity:
None of the ingredients is listed.
·
Carcinogenic categories
· EPA (Environmental Protection Agency)
None of the ingredients is listed.
· TLV (Threshold Limit Value)
None of the ingredients is listed.
· NIOSH-Ca (National Institute for Occupational Safety and Health)
None of the ingredients is listed.
·
GHS label elements The product is classified and labeled according to the Globally Harmonized System (GHS).
·
Hazard pictograms
·
Signal word Danger
· Hazard-determining components of labeling:
Acetic Acid, Glacial
· Hazard statements
Flammable liquid and vapor.
Causes severe skin burns and eye damage. May cause an allergic skin reaction.

15 Acetic Acid 99.8% HPLC Regulatory information

· Precautionary statements
Keep away from heat/sparks/open flames/hot surfaces. – No smoking. Keep container tightly closed.
Ground/bond container and receiving equipment.
Use explosion-proof electrical/ventilating/lighting/equipment. Use only non-sparking tools.
Take precautionary measures against static discharge. Do not breathe dusts or mists.
Wash thoroughly after handling.
Contaminated work clothing must not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. If swallowed: Rinse mouth. Do NOT induce vomiting.
If on skin (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove person to fresh air and keep comfortable for breathing.
If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Immediately call a poison center/doctor. Specific treatment (see on this label).
If skin irritation or rash occurs: Get medical advice/attention. Wash contaminated clothing before reuse.
In case of fire: Use CO2, powder or water spray to extinguish. Store in a well-ventilated place. Keep cool.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
·
Chemical safety assessment: A Chemical Safety Assessment has not been carried out.
*
This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship.
·
Department issuing SDS: Environment protection department.
Date of Preparation / Last Revision:
· Date of preparation / last revision
·
Creation date for SDS. 22/11/2018 STN
·
Revision 1.0, 19/03/2020: Reviewed SDS for accuracy. MH/STN
·
Revision 1.1, 06/03/2024 Reviewed SDS for accuracy. MH/STN
·
Revision 1.2, 20/01/2025: Reviewed SDS for accuracy. STN
16 Other information