n-Butanol 99.99% for HPLC Product identifier

TRADE NAME: N-BUTANOL 99.99% FOR HPLC & SPECTROSCOPY
Details of the supplier of the safety data sheet
Manufacturer/Supplier:
RLS Chemicals
32 Main Reef Road
Benrose, Johannesburg
2094
Emergency telephone number:
Spill Tech: 086 100 0366
Emergency: 010 448 3426
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· Classification of the substance or mixture
Flammable Liquids – H226
Acute Toxicity, Oral – H302
Skin Irritation – H315
Serious Eye Damage – H318
Specific Target Organ Toxicity, single exposure, Respiratory system, Central Nervous system – H335, H336
· Label elements
·
GHS label elements The substance is classified and labeled according to the Globally Harmonized System (GHS).
· Hazard pictograms
·
Signal word Danger
· Hazard statements
Harmful if swallowed.
Flammable liquid and vapor.
· Precautionary statements
Avoid breathing dust/fume/gas/mist/vapors/spray Wash thoroughly after handling.
Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area.
If swallowed: Call a poison center/doctor if you feel unwell. Rinse mouth.
IF INHALED: Remove person to fresh air and keep comfortable for breathing.

1 Identification
2 n-Butanol 99.99% HPLC Hazard(s) identification
Description of first aid measures
General information:
Symptoms of poisoning may even occur after several hours; therefore medical observation for at least 48 hours after the accident.
After inhalation:
Supply fresh air. If required, provide artificial respiration. Keep patient warm. Consult doctor if symptoms persist. In case of unconsciousness place patient stably in side position for transportation.
After skin contact: Generally the product does not irritate the skin.
After eye contact: Rinse opened eye for several minutes under running water.
After swallowing: Immediately call a doctor.
Information for doctor:
Most important symptoms and effects, both acute and delayed No further relevant information available.
Indication of any immediate medical attention and special treatment needed
No further relevant information available.
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4 First-aid measures
5 2 n-Butanol 99.99% HPLC Fire-fighting measures
· Extinguishing media
·
Suitable extinguishing agents: Use fire fighting measures that suit the environment.
·
Special hazards arising from the substance or mixture No further relevant information available.
(Contd. on page 3)
Other hazards
Results of PBT and vPvB assessment
PBT: Not applicable.
vPvB: Not applicable.
Health = 2
Fire = 1
Reactivity = 0
REACTIVITY 0
· HMIS-ratings (scale 0 – 4)
HEALTH 2
FIRE 1
Health = 2
Fire = 1
Reactivity = 0
1
2 0
Dispose of contents/container in accordance with local/regional/national/international regulations.
Classification system:
NFPA ratings (scale 0 – 4)
(Contd. of page 1)
Chemical characterization: Substances
CAS: 71-36-3
Butyl Alcohol
Min 99.99%
3 n-Butanol 99.99% HPLC Composition/information on ingredients

Personal precautions, protective equipment and emergency procedures Not required.
Environmental precautions: Do not allow to enter sewers/ surface or ground water.
Methods and material for containment and cleaning up:
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust). Ensure adequate ventilation.
Reference to other sections
See Section 7 for information on safe handling.
See Section 8 for information on personal protection equipment. See Section 13 for disposal information.
Protective Action Criteria for Chemicals
PAC-1: 30 ppm
PAC-2: 52 ppm
PAC-3: 740 ppm
Handling:
Precautions for safe handling Ensure good ventilation/exhaustion at the workplace.
Information about protection against explosions and fires: No special measures required.
Conditions for safe storage, including any incompatibilities
Storage:
Requirements to be met by storerooms and receptacles: No special requirements.
Information about storage in one common storage facility: Not required.
Further information about storage conditions: Keep receptacle tightly sealed.
Specific end use(s) No further relevant information available.
Additional information about design of technical systems: No further data; see section 7.
Control parameters
Additional information: The lists that were valid during the creation were used as basis.
Exposure controls
Personal protective equipment:
General protective and hygienic measures: Wash hands before breaks and at the end of work.
Breathing equipment:
In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use respiratory protective device that is independent of circulating air.
Protection of hands:
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/ the chemical mixture.

6 Accidental release measures
7 2 n-Butanol 99.99% HPLC Handling and storage

· Components with limit values that require monitoring at the workplace:
CAS: 71-36-3 Butyl alcohol
WEEL
Long-term value: 10 ppm

Advice for firefighters
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Protective equipment: Mouth respiratory protective device. 8 Exposure controls/personal protection
Information on basic physical and chemical properties
·
2 n-Butanol 99.99% HPLC General Information
·
Appearance:
Form: Liquid
Color: Colorless
·
Odor: Ethanolic
·
Odor threshold: Not determined.
· pH-value:
7 at 70 g/l at 20℃
· Change in condition
Melting point/Freezing Point: Boiling point/Boiling range:
-90℃
116-118℃
· Flash point:
35°C Pensky-Martens closed cup
· Flammability (solid, gaseous):
Not applicable.
· Auto igniting:
No data available.
· Decomposition temperature:
Not determined.
· Ignition temperature:
Not determined.
· Danger of explosion:
No data available.
· Explosion limits: Lower:
Upper:
1.4 Vol %
11.2 Vol %
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Vapor pressure at 20 °C:
< 10 hPa
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Density at 25 °C:
·
Relative density
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Vapor density
·
Evaporation rate
0.81 g/cm³
Not determined.
Not determined. Not determined.
· Solubility in / Miscibility with Water at 20 °C:
66 g/l
· Partition coefficient (n-octanol/water): log Pow: 1 at 25℃ – Bioaccumulation is not expected.
· Viscosity: Dynamic: Kinematic:
Not determined. Not determined.
(Contd. on page 5)
(Contd. of page 3)
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
·
Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer.
·
Penetration time of glove material
The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.
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Eye protection: Goggles recommended during refilling.
·
Body protection: Protective work clothing 9 Physical and chemical properties

2 n-Butanol 99.99% HPLC Information on toxicological effects
Acute toxicity:
Primary irritant effect:
on the skin: No irritant effect.
on the eye: No irritating effect.
Sensitization: No sensitizing effects known.
Additional toxicological information:
Carcinogenic categories
IARC (International Agency for Research on Cancer) Substance is not listed.
NTP (National Toxicology Program) Substance is not listed.
OSHA-Ca (Occupational Safety & Health Administration) Substance is not listed.
11 Toxicological information
Toxicity
Aquatic toxicity: No further relevant information available.
Persistence and degradability No further relevant information available.
Behavior in environmental systems:
Bioaccumulative potential No further relevant information available.
Mobility in soil No further relevant information available.
Additional ecological information:
General notes:
Water hazard class 1 (Assessment by list): slightly hazardous for water
Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system.
Results of PBT and vPvB assessment
PBT: Not applicable.
vPvB: Not applicable.
Other adverse effects No further relevant information available.
12 Ecological information
· Other information No further relevant information available.
· LD/LC50 values that are relevant for classification:
Oral LD50
790 mg/kg (Rat)

Reactivity No further relevant information available.
Chemical stability
Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
Possibility of hazardous reactions Risk of ignition or vapours with: aluminum, acid chlorides, alkali metals
Conditions to avoid Heating
Incompatible materials: No further relevant information available.
Hazardous decomposition products: No dangerous decomposition products known.
10 Stability and reactivity

14 2 n-Butanol 99.99% HPLC Transport information
Safety, health and environmental regulations/legislation specific for the substance or mixture
No further relevant information available.
Sara
Section 355 (extremely hazardous substances): Substance is not listed.
Section 313 (Specific toxic chemical listings): Substance is not listed.
TSCA (Toxic Substances Control Act): ACTIVE
Hazardous Air Pollutants Substance is not listed.
Proposition 65
Chemicals known to cause cancer: Substance is not listed.
Chemicals known to cause reproductive toxicity for females: Substance is not listed.
Chemicals known to cause reproductive toxicity for males: Substance is not listed.
(Contd. on page 7)
15 Regulatory information
· UN-Number
· DOT, IMDG, IATA UN1120
· UN proper shipping name
· DOT, IMDG, IATA BUTANOLS
· Transport hazard class(es)
· DOT, IMDG, IATA
· Class 3
· Label III
· Packing group
· DOT, IMDG, IATA III
· Environmental hazards:
· Marine pollutant: No
· Special precautions for user No data available
· Transport in bulk according to Annex II of
MARPOL73/78 and the IBC Code Not applicable.
UN “Model Regulation”: UN1 1 1 2 0 BUTANOLS, 3, III
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Waste treatment methods
Recommendation:
Must not be disposed of together with household garbage. Do not allow product to reach sewage system.
Uncleaned packagings:
Recommendation: Disposal must be made according to official regulations.
13 Disposal considerations

This information is based on our present knowledge. However, this shall not constitute a guarantee for any
specific product features and shall not establish a legally valid contractual relationship.
Department issuing SDS: Environment protection department.
Date of preparation / last revision
Creation date for SDS. 31/07/2023. STN
Revision 1.0: 12/12/2024: STN
16 2 n-Butanol 99.99% HPLC Other information
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· Chemicals known to cause developmental toxicity: Substance is not listed.
· Carcinogenic categories
· EPA (Environmental Protection Agency) Substance is not listed.
· TLV (Threshold Limit Value) Substance is not listed.
· NIOSH-Ca (National Institute for Occupational Safety and Health) Substance is not listed.
· GHS label elements The substance is classified and labeled according to the Globally Harmonized System (GHS).
· Hazard pictograms
· Signal word Danger
· Hazard statements
Harmful if swallowed.
Flammable liquid and vapor.
· Precautionary statements
Avoid breathing dust/fume/gas/mist/vapors/spray
Wash thoroughly after handling.
Do not eat, drink or smoke when using this product.
Use only outdoors or in a well-ventilated area.
If swallowed: Call a poison center/doctor if you feel unwell.
Rinse mouth.
IF INHALED: Remove person to fresh air and keep comfortable for breathing.
Dispose of contents/container in accordance with local/regional/national/international regulations.
· Chemical safety assessment: A Chemical Safety Assessment has not been carried out.